Innovation in interventional cardiology

Biomime Branch coronary stent for bifurcations

Dr. José R. Rumoroso


Older devices can be revived with innovative technological improvements. This is the case for the design of a stent specifically for bifurcations, now called Biomime Branch (Meril, India).

This is a chrome-cobalt stent with 65 µm strut thickness. It is covered with a resorbable PLGA-PLLA polymer that elutes sirolimus at a dose of 1.25 µg/mm2. The device’s architecture is interesting because it has a hybrid design, which is very useful for treating 1,1,1 bifurcations in which there is a very high probability of needing more than one stent. It is mounted on a balloon (with four radio-opaque markers) with a tapered design, which allows stent implantation from the main branch into the side branch. The proximal segment (which is positioned in the main branch) has a closed-cell design and the distal segment (for the side branch lesion) has an open-cell design. The distal segment has a variable length, from 6.5 to 13 mm, to ensure coverage of side branch lesions.

Between the two segments there is a transition zone with three panels with highly flexible connectors that leave large open spaces, allowing access to the main branch to implant a further stent without the risk of losing the side branch, and avoiding overexpansion of the stent at post-dilatation. This reduces the risk of losing important branches with severe lesions.

In my opinion, this is a very interesting device, as it simplifies the procedure, reduces the intervention time when it is likely that 2 stents will be implanted, and limits the amount of metal that may be exposed at the carina.

Palabras clave: Intervención coronaria percutánea, bifurcación coronaria, stent coronario para bifurcación, stent coronario liberador de droga. Keywords: Percutaneous coronary intervention, coronary bifurcation, bifurcation dedicated stent, drug eluting stent.